In these studies, involving about patients, analyses of patient diaries showed no effect of VIAGRA on rates of attempted intercourse about 2 per week , but there was clear treatment-related improvement in sexual function: per patient weekly success rates averaged 1. Your doctor will tell you not to take sildenafil if you are taking street drugs containing nitrates. It’s best to check your chosen provider’s site for more information. As in the other titration studies, patients were started on 50 mg and allowed to adjust the dose up to mg or down to 25 mg of VIAGRA; all patients, however, were receiving 50 mg or mg at the end of the study. The mean steady state volume of distribution Vss for sildenafil is L, indicating distribution into the tissues. Those with a history of blood pressure or heart issues, hormonal imbalances, mental health issues, and diabetes should consult their doctor before trying PDE5 inhibitors. Take sildenafil at around the same times every day.Generic Viagra (sildenafil) is available as a , , , and milligram (mg) pill and in liquid form. It’s meant to be taken as needed — about an hour before sex — but shouldn’t be. Headache, flushing, and upset stomach are common Viagra side effects. These effects are usually mild and often resolve on their own. While rare, Viagra can cause an erection that lasts longer than 4 hours (priapism). This can result in permanent damage if left untreated. Vision changes are also possible. The typical dose is to take 50 mg of sildenafil (Viagra) by mouth, about 1 hour before sex, as needed. The maximum recommended dose is mg. Don’t take sildenafil (Viagra) .