Do not expose this medication to direct sunlight or wet surfaces. Priligy is not indicated for use by women. If the patient experiences possibly prodromal symptoms, the patient should immediately lie down so his head is lower than the rest of his body or sit down with his head between his knees until the symptoms pass, and be cautioned to avoid situations where injury could result, including driving or operating hazardous machinery, should syncope or other CNS effects occur see Section 4. Intact dapoxetine and dapoxetine-N-oxide were the major circulating species in the plasma. This method works as follows: Begin sexual activity, including stimulating the penis, until you feel almost ready to ejaculate. Pain relievers.Priligy contains the active ingredient dapoxetine, which is a selective serotonin reuptake inhibitor (SSRI). It works by boosting the levels of serotonin in the body, causing a delayed reaction in the areas of the brain that cause ejaculation. This means it . Priligy is indicated for the treatment of premature ejaculation (PE) in adult men aged 18 to 64 years. Priligy should only be prescribed to patients who meet all the following criteria: • An intravaginal ejaculatory latency time (IELT) of less than two minutes; and. How to take dapoxetine tablets Before you start the treatment, read the manufacturer’s printed information leaflet from inside the pack. It will give Take dapoxetine exactly as your doctor tells you to. Drink a full glass of water at the same time as you take a tablet. Do not take more than one.