Tadalafil was approved in in the United States for the treatment of pulmonary arterial hypertension [28] and is under regulatory review in other regions for this condition. Resources and support See the Healthy Male site for more information about erectile dysfunction and its treatment. The FDA has also approved tadalafil for treatment of both benign prostatic hypertrophy and erectile dysfunction where the two conditions co-exist. Comparison with actions of other PDE5 inhibitors[ edit ] Sildenafil and vardenafil inhibit PDE6, an enzyme found in the eye, more than tadalafil. Taking Cialis does not mean you are guaranteed to get an erection.$ (save %) local_offer_outlined Avg retail price $ medication_outlined Availability Available See GoodRx coupons warning Are you looking for information on Adcirca (tadalafil) instead? What is Tadalafil (Cialis)? Drug Facts Common Brands Cialis Drug Class PDE-5 inhibitor. Cialis (branded Tadalafil) Cialis is a reliable, branded ED treatment that lasts up to 36hrs. Can be taken with food. Works in 30mins, lasts up to 36hrs. Works for 80% of men. 10mg 20mg. 4 tablets. Out of stock. 8 tablets.  · The typical dose for once-daily Cialis for ED is milligrams (mg) to 5 mg. When used as needed for ED, the usual Cialis dose is 10 mg (with a maximum daily dose of 20 mg). The typical dose of.