Finding an online ED provider can feel overwhelming. You take one 2. In some cases, ED can cause a strain on relationships and impact self-esteem. People taking nitrates like nitroglycerin Nitrostat or isosorbide mononitrate Imdur should not take PDE5 inhibitors, as doing so could result in a dangerous drop in blood pressure. It’s available in 50 mg, mg, and mg tablets. · 97% average discount Depression 86% average discount Hypertension 74% average discount Urinary Tract Infection 67% average discount Based on the average user savings between January and September Search for your prescription on our site or mobile app to see how much you can save. How GoodRx Works Compare . Sildenafil (Viagra) and tadalafil (Cialis) are the most commonly prescribed medications for ED, and they have the longest track record. For occasional use, most people start with sildenafil. For regular use, tadalafil can be a better fit. Some people prefer to alternate between medications. All ED meds are equally safe and effective. Sildenafil (Viagra) and tadalafil (Cialis) are the most commonly prescribed medications for ED, and they have the longest track record. For occasional use, most people start with sildenafil. For regular use, tadalafil can be a better fit. Some people prefer to alternate between medications. All ED meds are equally safe and effective.