In some patients, concomitant use of these two drug classes can lower blood pressure significantly [see Drug Interactions 7. Here are some key factors to consider when deciding: Pricing: Know how much your monthly supply will cost with shipping and tax. Was this article useful? We considered cost, medications available, and whether generic versions were offered to help reduce costs. If your prescription is for Cialis Daily, it can help to take it at the same time each day to maintain a steady level of tadalafil in your body. Therefore, physicians should inform patients that substantial consumption of alcohol e.$. Total: $. Contact. After taking a single tablet, some of the active ingredient of Cialis remains in your body for more than 2 days. Cialis is a brand of tadalafil, one of the most popular medications to treat erectile dysfunction (ED).It was first approved in Cialis and generic tadalafil are available in four different strengths— mg, 5 mg, 10 mg and 20 mg—but which one should you take? If you’ve never tried Cialis before, your doctor will likely start you on a low dose, like mg or 5 mg. The 20 mg tablet is the highest strength and is often not preferred because it has the potential to. 8 tablets Out of stock Out of stock 16 tablets Out of stock Out of stock One-time or subscription How to take Tadalafil Take one tablet at least 30 minutes before sex. Effects can last for up to 36 hours. Never take more than one tablet within 36 hours. Alcohol will limit Tadalafil’s effectiveness. Do not combine Tadalafil with other ED medicines.